Female Pharmaceutical Intermediates Steroid Estradiol Cypionate
Depofemin for Injection 313-06-4
17-cyclopentanepropanoate Formula: C26H36O3 Synonyms:
MSDS: 313-06-4 MSDS download
CAS No: 313-06-4
Molecular Weight: 396.62
Density: 1.15 g/cm3
Melting Point: 149-153 °C
Boiling Point: 532.8 °C at 760mmHg
Flash Point: 207.7 °C
Solubility: insoluble in water
Appearance: White or off-white crystalline powder
Packing: 1kg/aluminum foil bag
Estradiol cypionate is used for:
Treating certain symptoms of menopause (eg, hot flashes, vaginal
itching, burning, or dryness). It is used to treat low levels of
estrogen caused by certain conditions. It may also be used for
other conditions as determined by your doctor.
Estradiol cypionate is a female estrogen hormone. It works by
replacing natural estrogens in a woman who can no longer produce
Do NOT use estradiol cypionate if:
you are allergic to any ingredient in estradiol cypionate
you are pregnant or suspect you may be pregnant, or you have
vaginal bleeding of abnormal or unknown cause
you have known or suspected breast cancer or any other
you have any other estrogen-dependent cancer
you have the blood disease porphyria, or a history of blood clots
or liver problems
you have had a recent (within the past year) stroke or heart attack
Contact your doctor or health care provider right away if any of
these apply to you.
How to use estradiol cypionate:
Use estradiol cypionate as directed by your doctor. Check the label
on the medicine for exact dosing instructions. Check the label on
the medicine for exact dosing instructions.
An extra patient leaflet is available with estradiol cypionate.
Talk to your pharmacist if you have questions about this
Estradiol cypionate is usually given as an injection at your
doctor's office, hospital, or clinic. If you will be using
estradiol cypionate at home, a health care provider will teach you
how to use it. Be sure you understand how to use estradiol
cypionate. Follow the procedures you are taught when you use a
dose. Contact your health care provider if you have any questions.
Do not use estradiol cypionate if it contains particles, is cloudy
or discolored, or if the vial is cracked or damaged.
Keep this product, as well as syringes and needles, out of the
reach of children and pets. Do not reuse needles, syringes, or
other materials. Ask your health care provider how to dispose of
these materials after use. Follow all local rules for disposal.
If you miss a dose of estradiol cypionate, use it as soon as
possible. If it is almost time for your next dose, skip the missed
dose and go back to your regular dosing schedule. Do not use 2
doses at once.
Ask your health care provider any questions you may have about how
to use estradiol cypionate.
Important safety information:
Estradiol cypionate may cause dizziness. This effect may be worse
if you take it with alcohol or certain medicines. Use estradiol
cypionate with caution. Do not drive or perform other possibly
unsafe tasks until you know how you react to it.
Limit alcoholic beverages while you are using estradiol cypionate.
Estradiol cypionate may cause dark skin patches on your face
(melasma). Exposure to the sun may make these patches darker and
you may need to avoid prolonged sun exposure and sunlamps. Consult
your doctor regarding the use of sunscreens and protective
Estradiol cypionate may increase the risk of blood clots. The risk
may be greater if you smoke (especially in women older than 35
years of age).
Contact your health care provider if vaginal bleeding of unknown
cause occurs. This could be a sign of a serious condition requiring
immediate medical attention.
Contact your health care provider if vaginal discomfort occurs or
if you suspect you have developed an infection while taking
Follow your doctor's instructions for examining your breasts, and
report any lumps immediately.
If you wear contact lenses and you develop problems with them,
contact your doctor.
If you will be having surgery or will be confined to a chair or bed
for a long period of time (eg, a long plane flight), notify your
doctor beforehand. Special precautions may need to be taken in
these circumstances while you are taking estradiol cypionate.
Diabetes patients - Estradiol cypionate may affect your blood
sugar. Check blood sugar levels closely. Ask your doctor before you
change the dose of your diabetes medicine.
Estradiol cypionate may interfere with certain lab tests. Be sure
your doctor and lab personnel know you are using estradiol
Discuss with your doctor every 3 to 6 months whether treatment with
estradiol cypionate is still appropriate.
Lab tests, including physical exams and blood pressure, may be
performed while you use estradiol cypionate. You should have breast
and pelvic exams, and a Pap test at least once a year. You should
also have periodic mammograms as determined by your doctor. Be sure
to keep all doctor and lab appointments.
Estradiol cypionate should not be used in CHILDREN; safety and
effectiveness in children have not been confirmed.
PREGNANCY and BREAST-FEEDING: Do not use estradiol cypionate if you
are pregnant. Avoid becoming pregnant while you are taking it. If
you think you may be pregnant, contact your doctor right away.
Estradiol cypionate is found in breast milk. If you are or will be
breast-feeding while you use estradiol cypionate, check with your
doctor. Discuss any possible risks to your baby.
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