2mg / Vial MGF Mechano Polypeptide Hormones for Muscle Building
Synonyms:MGF(Mechanical growth factor)
Unit Size :2 mg/vial, 5mg/vial, 10mg/vial
Unit Quantity :1 Vial
Molecular Formula :C121H200N42O39
Molecular Weight :2867.14
Appearance :White Powder
Identity (ESI-MS) :2867.14±3.7
Source :Chemical Synthesis
Storage :Lyophilized MGF is stable at room temperature for 90
days,however it should be stored in a freezer below -8C for any
extended period of time. After reconstituting MGF should be
refrigerated at temperatures not to exceed 36 F.
It was first discovered in the muscle by Goldspink, et al. In human
muscle, a 49-base insert changes the reading frame in mechano
growth factor (MGF) as compared to IGF-1.
When mechanical overload is introduced to a muscle (as by weight
training), the IGF-1 gene released and is differentially spliced
during the bodies response. Initially, it it is spliced to produce
predominantly IGF-1Ec (called the MGF splice variant of IGF-1).
This early splicing stimulates satellite cells into activation.
Which in turn allows the activation of extra undamaged nuclei to
grow new muscle fiber and tissue. The appearance of MGF also
initiates the upregulation of new protein synthesis. After this
initial splicing of IGF-1 into MGF, production then switches
towards producing a systemic release of IGF-1Ea from the liver,
which also upregulates protein synthesis as well. The expression of
IGF-1 splice variants, over the course of the healing and regrowth
phase of muscle repair is thought to be the primary anabolic
mechanism by which the body produces new muscle. MGF is available
as an injectable peptide, and it has been anecdotally shown that
injecting it will cause a response in the area resulting in
localized muscle growth.
CJC-1295 with DAC(2mg/vial)
CJC-1295 without DAC(2mg/vial)
pentadecapeptide BPC 157(2mg/vial)
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